Rheumatology Medical News about behcets disease;clinical characteristics

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Epidemiology and clinical characteristics of Behçets disease in the US: A population-based study
Arthritis Care and Research , 05/06/09

Calamia KT et al. – Study demonstrates an overall incidence of 0.38 per 100,000 population for Behçet's disease (BD) in Olmsted County, Minnesota, which is comparable with other Western populations. The prevalence of 5.2 per 100,000 population is reported in Western countries, which is lower than that in countries along the Silk Road.

Methods

Study describes the incidence and prevalence of BD in Olmsted County, Minnesota over 45 yrs
Subjects: ≥18 yrs with a clinical diagnosis of and/or ISG criteria for BD from Jan 1, 1960 to Jan 1, 2005
Age- and sex-specific incidence and prevalence were estimated
Age- and sex-adjusted to the 2000 US total population

Results

Study population: 13 subjects with BD; 11 fulfilled ISG criteria between 1960 and 2005
Mean age: 31 yrs; 69% were white
Point prevalence in 2000 was 5.2 per 100,000 population
Overall annual age- and sex-adjusted incidence of BD was 0.38 per 100,000 population, with a higher incidence in women than in men
Dermatologic lesions included oral ulcers (100%), genital ulcers (62%), erythema nodosum (46%), and papulopustular lesions (54%)
Ocular lesions, vascular complications, and central nervous system involvement were present in 8, 3, and 3 subjects, respectively

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