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The alpha-7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation
Arthritis & Rheumatism, 05/06/09
Van Maanen MA et al. - The alpha-7nAChR and its dup-alpha-7 variant are expressed in RA synovium, where they may play a critical role in regulating inflammation. Targeting the alpha-7nAChR could provide a novel antiinflammatory approach to the treatment of RA.
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Today in Basic Science/Genetics...keeping you current
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Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
Rheumatology, 12/20/09
The 'RASor's' edge: Ras proteins and matrix destruction in arthritis
Arthritis Research & Therapy, 12/19/09
Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation
Journal of Rheumatology, 12/17/09
Today in Rheumatoid Arthritis...keeping you current
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Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study
Arthritis Research & Therapy, 12/19/09
Update on the genetic risk factors for rheumatoid arthritis
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The diagnostic utilities of anti-agalactosyl IgG antibodies, anti-cyclic citrullinated peptide antibodies, and rheumatoid factors in rheumatoid arthritis
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