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See Latest ArticlesAssociation of various inflammatory diseases with human leukocyte antigens B27, B7, Bw4 and Bw6 in patients with SSA
Rheumatology International, 04/29/09
Singh S et al. – Study concludes that microbial infections do have some pathogenic role in causing seronegative spondyloarthopathy (SSA).
Methods- Aim was to study the association of HLA B27, B7, Bw4 and Bw6 with some inflammatory diseases, in SSA pts
- 220 SSA pts were studied
- HLA typing for these antigens were done by the complement-mediated microcytotoxicity method
- Total positivity of B27 was found to be 68.64% in SSA pts
- Tubercular infection and acute anterior uveitis were statistically significant in B27-positive SSA pts
- Tuberculosis was also significantly associated with Bw4
- In SSA urinary tract infection, gastrointestinal infection and streptococcal infection were not associated with B27, B7, Bw4 or Bw6 antigens
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Today in Basic Science/Genetics...keeping you current
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Increased mRNA expression of collagen V gene in pulmonary fibrosis of systemic sclerosis
European Journal of Clinical Investigation, 12/04/09
The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome
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Today in Spondylarthropathies...keeping you current
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An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population
Scandinavian Journal of Rheumatology , 11/24/09
The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene TRADD (TNF receptor type 1-associated death domain)
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