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See Latest ArticlesFibromyalgia pain and its modulation by hypnotic and non-hypnotic suggestion: An fMRI analysis
European Journal of Pain, 04/30/09
Derbyshire SWG aet al. – Data provide evidence for the greater efficacy of suggestion following a hypnotic induction. They also indicate direct involvement of a network of areas widely associated with the pain ‘neuromatrix’ in fibromyalgia pain experience. These findings provide direct evidence that regions involved in pain experience are actively involved in the generation of fibromyalgia pain.
Methods- Aim was to investigate if suggestion w/o hypnosis is equally effective to modulate the subjective experience of pain in fibromyalgia
- Suggestions following a hypnotic induction and the same suggestions w/o a hypnotic induction were used during functional MRI to increase and decrease the subjective experience of fibromyalgia pain
- Suggestion in both conditions resulted in changes in reported pain experience, although pts claimed more control over their pain and reported greater pain reduction when hypnotized
- Activation of midbrain, cerebellum, thalamus, and midcingulate, primary and secondary sensory, inferior parietal, insula and prefrontal cortices correlated with reported changes in pain with hypnotic and non-hypnotic suggestion
- These activations were of greater magnitude when suggestions followed a hypnotic induction in cerebellum, anterior midcingulate cortex, anterior and posterior insula and the inferior parietal cortex
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