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The fibromyalgia syndrome: Translating science into clinical practice
Journal of Musculoskeletal Pain , 04/22/09

Henriksson KG - The biological part of fibromyalgia syndrome (FMS) reflects a long-standing or permanent change in the function of the nociceptive nervous system, that can be equated with a disease. It is hoped that upgrading FMS from illness to disease will increase the awareness of FMS among health personnel.

Methods

Objectives of this study were to:
- present the arguments in favor of considering the biological component of the FMS, a disease of the nociceptive nervous system
- present reliable methods for diagnosing such a disease

Results

Studies confirm that there is long-standing or permanent pain hypersensitivity in FMS
The main causes of the pain amplification are:
- central and peripheral sensitization of pain transmission neurons and/or
- pain disinhibition due to a disturbed endogenous pain modulation
Measure of pressure-pain thresholds and degree of pain perception: manual palpation method to determine the no. of tender joint
Pain perception is influenced by psychological factors

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