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Willingness-to-pay stated preferences for 8 health-related quality-of-life domains in psoriatic arthritis: A pilot study
Seminars in Arthritis and Rheumatism, 04/16/09

Hu SW et al. – Study reports that “willingness-to-pay” (WTP) is a novel quantitative patient-perspective measure that captures the complex manifestations of psoriatic arthritis (PsA) and its impact on the individual, allowing the quantification of specific HR-QOL parameters and provides potential for comparison across various disease processes.

• Study was conducted to pilot a novel application of WTP as a Patient Reported Outcome to measure the relative impact of PsA in 8 domains of HR-QOL
• 59 PsA pts were interviewed on 8 WTP HR-QOL domains
• Participants were asked to rank the 8 domains in order of HR-QOL impact
• In each domain, participants were asked:
  • whether PsA affected that domain
  • whether they were willing to pay for a cure in that domain
  • and the amount they were willing to pay
• Median WTP amounts were compared with the proportion of participants affected by and willing to pay in each domain
• Responses in US dollars were interpreted as strength of preference rather than absolute monetary values

• 98% were white, 70% were ≥45 yrs, 98% were insured, and 66% earned >$65,000/yr
• Physical domain was most affected by PsA
• Intimacy and concentration were ranked lowest
• Participants reported a wide range of WTP amounts ($0 to $1,000,000)
• Median WTP amounts were highest in the physical, work, sleep, and self-care domains
• Related domains elicited median WTP amounts that were highly correlated
• No differences in median WTP amounts were found across ages, genders, and income levels for the different domains

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