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Fixed digital contractures revealing light-chain amyloidosis
Joint, Bone, Spine, 04/21/09
Costantino F et al. - The authors describe the case of a 72-year-old woman who was referred to their rheumatology department for fixed flexion contractures of the fingers that developed concomitantly with a decline in general health. Macroglossia and recent-onset dyspnea were noted. Investigations, which included a tongue biopsy, established the diagnosis of kappa light-chain amyloidosis with soft tissue, bone, and cardiac deposits.
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