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See Latest ArticlesOutcome and predictor relationships in fibromyalgia and rheumatoid arthritis: Evidence concerning the continuum versus discrete disorder hypothesis
Journal of Rheumatology, 04/08/09
Wolfe F et al. – Data supports the hypothesis that fibromyalgia (FM) is the end of a severity continuum, but that additional psychological factors are an integral part of the syndrome.
Methods- Study was undertaken to:
- compare outcome-predictor relationships in FM and RA
- to provide information regarding the competing hypotheses that FM is a continuum or a discrete disorder
- 3 outcome variables studied: work disability, opioid use, depression; and 12 clinical predictor variables
- 2,046 pts with FM and 20,374 with RA
- All measures of status and outcome were more abnormal in FM than in RA
- Depression was reported in 33.4% of pts with FM vs 15.1% of those with RA
- The predictor-outcome relationship was stronger in RA in 28/36 tests, and not different in the remainder
- Relationship between outcome and predictor variables was generally similar in pts with FM and RA
- However, unmodeled depression that was not explained by study variables was noted in FM
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Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: A systematic review
Journal of Pain Research, 11/30/09
Clinical Aspects and Management of Fibromyalgia Syndrome
Annals, Academy of Medicine, Singapore, 11/30/09
Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF &alpha), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia
Clinical Rheumatology, 11/24/09
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