Rheumatology

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Quality of life in patients with systemic sclerosis compared to the general population and patients with other chronic conditions
Journal of Rheumatology, 04/13/09

Hudson M et al. – Study reports that health-related quality of life (HRQOL) of patients with systemic sclerosis (SSc) is significantly impaired compared to that of the general population and is comparable to or worse than that of patients with other common chronic conditions.

• Aim was to compare HRQOL of SSc pts with individuals in the general population and pts with other common chronic diseases
• HRQOL of SSc pts in the Canadian Scleroderma Research Group registry was measured using SF-36
• Results were compared to US general population norms and scores reported for pts with heart disease, lung disease, hypertension, diabetes, and depression

• SF-36 scores were available for 504 SSc pts; 86% women, mean age 56 yrs, mean disease duration 11 yrs
• Greatest impairment in SF-36 subscale scores were in the physical functioning, general health, and role physical domains
• SF-36 subscale and summary scores in SSc were worse vs US general population norms for women of similar ages, except for mental health and mental component summary score
• They were generally comparable to or worse than the scores of pts with other common chronic conditions

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