Rheumatology Medical News about peripheral arterial disease;polymyalgia rheumatica

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Increased risk of peripheral arterial disease in polymyalgia rheumatica: A population-based cohort study
Arthritis Research & Therapy, 04/06/09

Warrington KJ et al. - Study concludes that patients with polymyalgia rheumatica (PMR) appear to have an increased risk of peripheral arterial disease (PAD).

Methods

Aim was to determine whether pts with PMR are at an increased risk of PAD
Pts with PMR between 1/1/1970 and 12/31/1999, were compared to non-PMR subjects
Both cohorts followed longitudinally by complete medical record review until death, incident PAD, migration, or 12/31/2006
PMR-related disease characteristics, traditional CV risk factors and diagnosis of PAD were abstracted from the medical record

Results

353 PMR pts, and 705 non-PMR subjects were followed for a median of 11.0 yrs
PAD developed in 38 pts with PMR and in 28 non-PMR subjects
After adjusting for traditional CV risk factors, pts with PMR still had a higher risk for PAD vs controls
Giant cell arteritis occurred in 18% PMR pts but was not predictive of PAD
No difference between mortality in PMR and the non-PMR cohorts nor in PMR pts with and those w/o PAD

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