Rheumatology Medical News about juvenile localized scleroderma;health-related quality of life

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Orzechowski NM et al. – Study reports that juvenile localized scleroderma (JLS) patients have some impairment in skin disease-specific health-related quality of life (HRQOL) when compared with a healthy reference population, but not as severe as that seen in atopic dermatitis (AD) patients.

Methods

Aim was to examine HRQOL of children with JLS and to compare them with patients with AD and healthy controls
81 JLS pts; age- and sex-matched 75 AD pts and 75 healthy controls
All pts were mailed a survey of KINDL and CDLQI
Linear regression models, adjusted for age and sex, examined differences in the KINDL and CDLQI scores

Results

Survey completion rates in JLS, AD and healthy control groups were 40, 28 and 44%, respectively
No difference in KINDL scores between JLS vs AD, and JLS vs healthy controls
However, CDLQI scores showed some impairment in HRQOL in JLS pts vs healthy reference population, but not to the degree seen in AD
HRQOL did not differ among the types of JLS with either measure

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