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See Latest ArticlesLack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis
Arthritis & Rheumatism, 04/13/09
Classen JF et al. - Purified IgG samples from patients with SSc were positive when tested for antinuclear autoantibodies, but did not specifically activate PDGFR-alpha or PDGFR-beta in any of the tests. Cell stimulation with PDGF itself consistently produced a strong signal.
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Long-term outcome of systemic sclerosis-associated pulmonary arterial hypertension treated with bosentan as first-line monotherapy followed or not by the addition of prostanoids or sildenafil
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