Rheumatology Medical News about systemic sclerosis;pulmonary arterial hypertension

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Genetics of systemic sclerosis-associated pulmonary arterial hypertension: Recent progress and current concepts
Current Rheumatology Reports, 03/27/09

Shah SJ et al. - Pulmonary arterial hypertension (PAH), a complication of systemic sclerosis (SSc) has no screening tests for early detection and is still identified late in the course of disease. Moreover the underlying mechanisms of SSc-associated PAH are poorly understood. Understanding the genetic differences between those patients with SSc who do and do not develop PAH may improve the ability to identify and treat patients earlier in the course of disease. Study highlights the important opportunities and challenges for exploration of genetics of PAH in SSc.

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Current concepts in disease-modifying therapy for systemic...

Measures of Response in Clinical Trials of Systemic Sclerosis: The Combined Response Index for Systemic Sclerosis (CRISS) and Outcome Measures in Pulmonary Arterial Hypertension Related to Systemic Sclerosis (EPOSS)
Journal of Rheumatology, 10/15/09 Relevance Score: 72%

Necrotizing fasciitis in a patient with overlap syndrome of systemic sclerosis and systemic lupus erythematosus
Rheumatology International, 11/16/09 Relevance Score: 68%

Aerobic Exercise is Safe and Effective in Systemic Sclerosis
International Journal of Sports Medicine, 10/14/09 Relevance Score: 67%

High frequency ultrasound measurement of digital dermal thickness in systemic sclerosis
Annals of Rheumatic Diseases, 10/23/09 Relevance Score: 66%

Mechanisms of vascular damage in systemic sclerosis
Autoimmunity, 10/02/09 Relevance Score: 66%