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See Latest ArticlesIncreased Expression of Toll-like Receptors in Aseptic Loose Periprosthetic Tissues and Septic Synovial Membranes Around Total Hip Implants
Journal of Rheumatology, 03/26/09
Tamaki Y et al. - Peri-implant tissues were well equipped with TLR in both aseptic and septic conditions. TLR 2- and TLR 5-mediated responses seemed to dominate. In aseptic loosening, monocytes/ macrophages were the main TLR-equipped cells apparently responsible for alarmin-induced responses. This could lead to production of inflammatory cytokines and extracellular matrix-degrading proteinases after phagocytosis of wear debris derived from an implant, but in septic cases they eventually respond to microbial components. Thus, inflammatory cells in both aseptic and septic tissues were equipped with TLR, providing them with responsiveness to both endogenous and exogenous TLR ligands.
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Factors associated with persistence of arthralgia among chikungunya virus-infected travellers: Report of 42 French cases
Journal of Clinical Virology, 12/14/09
Detection of Chlamydia trachomatis- DNA in synovial fluid: evaluation of the sensitivity of different DNA extraction methods and amplification systems
Arthritis Research & Therapy, 11/25/09
CD23 mediates anti-mycobacterial activity of human macrophages
Infection and Immunity, 10/20/09
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