Rheumatology

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Assessment of patients with fibromyalgia syndrome
Journal of Musculoskeletal Pain , 03/24/09

Mease PJ et al. - This article reviews the developments in assessment of fibromyalgia syndrome (FMS) including the determination and prioritization of key domains that constitute the syndrome and their performance characteristics of outcome measures.

• Review to describe the current state of consensus on the key clinical domains which constitute FMS
• Both the clinician and patient perspective, and the outcome measures were used to assess these domains in clinical research

• Both clinicians and pts concurred that key domains which constitute the experience of FMS and should be assessed in clinical research include:
  • pain, fatigue, sleep disturbance
  • multidimensional function, health-related quality of life
  • mood disturbance, and problems with cognition
• In addition, clinicians are concerned about assessing treatment side effects
• Pts feel that stiffness should be assessed
• Most of these domains, save dyscognition and stiffness, are currently being assessed
• Performance quality of these instruments is reviewed
• Areas in which further research and development is needed to improve the assessment is described
• Other areas of methodologic research include:
  • the establishment of “minimal clinically important difference” thresholds for outcome measures
  • and the development of a composite responder index for FMS

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