Rheumatology Journals

Rheumatology

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Clauw DJ et al. - Mechanistic studies reveal a number of neurobiological abnormalities in FMS that would be expected to lead to pain and/or sensory amplification, and clinical trials of drugs aimed at these targets have yielded the expected positive results. These trials suggest that different subgroups of patients may respond to different drugs, and that some patients may benefit from the concurrent use of education, cognitive-behavioral, and exercise programs that address comorbid problems often seen in FMS patients.

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