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Intravenous lidocaine for fibromyalgia syndrome: An open trial
Clinical Rheumatology, 03/17/09

Schafranski MD et al – Findings suggest that intravenous lidocaine infusions are safe and effective in the management of fibromyalgia.

• Study investigates the effect of iv infusions of lidocaine in pain and QoL of pts (n=23) with fibromyalgia
• 5 sequential iv 2% lidocaine infusions with rising dosages (2–5 mg/kg, d 1–5)
• Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a VAS for pain were applied before the first lidocaine infusion, immediately after the fifth infusion and 30 days after the fifth infusion

• An improvement was observed in FIQ scores after the fifth infusion, which was maintained after 30 d
• Similar results were seen concerning the VAS

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