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See Latest ArticlesThe E693 delta Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid beta Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells
American Journal of Pathology, 02/25/09
Nishitsuji K et al. - Results suggest that mutant A beta induces alteration of A beta trafficking and subsequent ER stress-induced apoptosis via enhancement of its intracellular oligomerization. Findings suggest that A beta oligomers exhibit toxicity in the extracellular space and within the cells themselves.
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The HAQ Compared with the MDHAQ: Keep It Simple, Stupid (KISS), with Feasibility and Clinical Value as Primary Criteria for Patient Questionnaires in Usual Clinical Care
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