Rheumatology

Your Article Summary

See Latest Articles

Renal AA amyloidosis: Survey of epidemiologic and laboratory data from one nephrology centre
International Urology and Nephrology, 02/06/09

Potyšová Z et al. – Study documents that although for approximately half of renal amyloidosis patients different treatment regimens could lead to a partial remission or disease stabilization, the prognosis of pts with amyloidosis could be regarded as unsatisfactory.

• An analysis of the laboratory and clinical data from pts with bioptically proven renal amyloidosis

• Renal amyloidosis was found in 99 pts (4.65%) from an overall number of 2,128 renal biopsies (RB) performed during a period of 11 yrs (from 1995 to 2006)
• AA amyloidosis was diagnosed in 46 pts
• Nephrotic syndrome was diagnosed in 27 pts (59%) with AA amyloidosis; all had different degrees of proteinuria
• Impaired renal function was discovered in 52%; in 6.5% renal replacement therapy was started
• Pts were treated with corticosteroids, DMARDs, and biological therapy in various regimens
• 19.5% died during the one-year f/u period; complications such as sepsis and cardiac failure were the leading causes of death
• Median survival in the AA group was 54 mo

Today in Amyloidosis...keeping you current

Receive free subspecialty "5-minute updates" via email

Left Ventricular Ejection Time on Echocardiography Predicts Long-Term Mortality in Light Chain Amyloidosis
Journal of the American Society of Echocardiography, 11/04/09

Amyloid arthropathy mimicking seronegative rheumatoid arthritis in multiple myeloma: case reports and review of the literature
Amyloid The Journal of Protein Folding Disorders, 11/18/09

Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome
Hypertension Research, 11/12/09

See All of Amyloidosis