Rheumatology Medical News about systemic sclerosis;time to diagnosis

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Time to diagnosis in systemic sclerosis: Is sex a factor?
Arthritis Care and Research , 02/03/09

Hudson M et al. - In systemic sclerosis (SSc), the time to diagnosis is longer for women than men after the onset of Raynaud's phenomenon, suggesting that there may be possible biologic differences in the progression of disease or in the health care trajectories.

Methods

Aim was to determine whether sex plays a role in the time to diagnosis of SSc
Dates of onset of Raynaud's phenomenon, the first non-Raynaud's disease symptom, and diagnosis were recorded
Association between sex and time to diagnosis was assessed

Results

408 pts; 347 women, 61 men, 44% with diffuse cutaneous SSc
Time to diagnosis after the onset of Raynaud's phenomenon was longer for women than men
However, they were not different after the onset of first non-Raynaud's disease manifestation
Time to diagnosis from onset of Raynaud's phenomenon was also longer for women than men with dc-SSc
Longer period between onset of Raynaud's phenomenon and SSc diagnosis was observed in women vs men with limited cutaneous SSc
No sex difference in time to diagnosis after the onset of first non-Raynaud's disease manifestation

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