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Leg ulcer in mixed connective tissue disease
Zeitschrift für Rheumatologie, 01/30/09
Becker H et al. - Authors describe a 35-year-old woman with mixed connective tissue disease who suffered from leg ulcers refractory to iloprost. When the patient was treated with the selective endothelin A receptor antagonist sitaxsentan for pulmonary arterial hypertension, the ulcers improved within 4 weeks and resolved completely thereafter.
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