Rheumatology Medical News about chronic Lyme disease;psychiatric comorbidity

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Role of psychiatric comorbidity in chronic Lyme disease
Arthritis Care and Research , 12/02/08

Hassett AL et al. – Psychiatric comorbidity and other psychological factors distinguished chronic Lyme disease (CLD) patients from other patients commonly seen in Lyme disease referral centers, and were related to poor functional outcomes.

Methods

Study to evaluate the prevalence and role of psychiatric comorbidity and other psychological factors in CLD pts
159 pts, screened for common axis I psychiatric disorders and axis II personilty disorders
Physician blind to psychiatric assessment results performed a medical evaluation
Two groups of CLD pts were compared with 2 groups of pts w/o CLD

Results

Axis I psychiatric disorders were more common in CLD pts, but personality disorders were not
Pts with CLD had higher negative affect, lower positive affect, and a greater tendency to catastrophize pain
All psychological factors except personality disorders were related to level of functioning
A predictive model based on these psychological variables was confirmed
Fibromyalgia was diagnosed in 46.8% of CLD pts

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