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Septic arthritis and acute hematogenous osteomyelitis in childhood at a tertiary hospital in Japan
Pediatrics International, 11/24/08

Yamagishi Y et al. – In pediatric patients with septic arthritis (SA), selection and administration of effective antibiotics is necessary, not only to cure the current infection but also to prevent metastatic infection.

Methods

Study to describe the clinical features of SA and acute hematogenous osteomyelitis (AHO) in children
Review of medical records of children presenting to Osaka City General Hospital with SA and AHO
Data assessed: location at onset, age and gender, risk factors, involved joints and/or bones, symptoms and time of presentation, causative agents and sensitivity to antibiotics, treatments and late complications

Results

There were 4 health-care-associated (HCAI) and 20 community-acquired infections (CAI)
Latency period from initial presentation to diagnosis was relatively longer in HCAI than CAI
Most common pathogen was methicillin-resistant Staphylococcus aureus (MRSA)
20% of CAI pts and half of the HCAI pts were treated empirically for MRSA
All pts with complications had MRSA infection

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