Rheumatology Medical News about gout; risk of Parkinson's disease

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Gout and the risk of Parkinson's disease: A cohort study
Arthritis Care and Research , 11/03/08

Vera MD et al. - Data provide evidence for a protective effect of gout on the risk of Parkinson's disease (PD) and support the purported protective role of uric acid.

Methods

Study to examine the relationship between gout and the risk of PD in people age ≥65 yrs
A population-based cohort study; incidence rates of PD between 11,258 gout pts and 56,199 controls were compared
Relative risk (RR) of PD was studied, adjusting for age, sex, prior comorbid conditions, and use of diuretics and NSAIDs

Results

Over an 8-yr median f/u, 1,182 new cases of PD were identified
Compared with individuals w/o gout, the multivariate RR of PD among those with gout was 0.70
Inverse association was similarly present in both sexes, and who did not use diuretics, but not among diuretic users

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