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Rheumatology

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Crawford M et al. - Rheumatoid arthritis patients are at heightened risk for infections because of intrinsic disease severity with associated inflammation, comorbid illnesses, and use of glucocorticoids and various immunosuppressives. Based on available evidence, an excess risk for infection occurs early after initiation of tumor necrosis factor-[alpha] inhibitor therapy. Additionally, special circumstances such as surgical procedures may increase infection risk.

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