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See Latest ArticlesIdentification of fibronectin type I domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs
Amyloid The Journal of Protein Folding Disorders, 10/28/08
Maas C et al. - Authors demonstrated that the isolated fibronectin type I domain inhibits amyloid-induced aggregation of blood platelets. The identification of the fibronectin type I domain as an amyloid-binding module provides new insights into the (patho-) physiological role of tPA and the homologous proteins which may offer new targets for intervention in amyloid pathology.
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