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See Latest ArticlesDisease severity in children and adolescents with Familial Mediterranean Fever: A comparative study to explore environmental effects on a monogenic disease
Annals of Rheumatic Diseases, 10/01/08
Ozen S et al. - Familial Mediterranean Fever (FMF) is worldwide the most common autoinflammatory disease. It has been suggested that environmental factors affect the phenotype since some patients do not develop the complication of secondary amyloidosis. Authors believe the modified scores that they introduce can be widely used for children. Results suggest that the environment affects the phenotype of a monogenic disease of the innate inflammatory pathway.
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