Rheumatology

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Risk factors for low BMD in healthy men age 50 years or older: A systematic review
Osteoporosis International, 09/05/08

Papaioannou A et al. - Risk factors for low bone mineral density (BMD) and bone loss in healthy men age 50 years or older are age, smoking, low weight, physical/functional limitations, and previous fracture.

• Objective was to examine risk factors for BMD and bone loss in healthy men age ≥50 yrs
• A systematic search in MEDLINE, Cochrane Database of Systematic Reviews, DARE, CENTRAL, CINAHL and Embase, Health STAR

• 299/642 screened articles required a full review, and 25 remained in the final assessment
• Consistent risk factors for low BMD/bone loss were: advancing age, smoking, and low weight/weight loss
• Physical/functional limitations and prevalent fracture were also associated with low BMD/bone loss
• Evidence was inconsistent or weak for physical activity, alcohol consumption, calcium intake, muscle strength, family history of fracture/osteoporosis, and height/height loss

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