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Long-term risk of myelodysplasia in melphalan-treated patients with immunoglobulin light-chain amyloidosis
Haematologica, 09/05/08
Gertz MA et al. - The objective of this study was to determine the risk of myelodysplasia after treatment with melphalan for patients with amyloidosis. The actuarial risk of myelodysplasia development at ten years was 18%. As the survival of patients with plasma cell disorders improves, myelodysplasia may be a more common cause of morbidity and mortality for this group.
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