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See Latest ArticlesRole of oxidative stress in the renal abnormalities induced by experimental hyperuricemia
American Journal of Physiology: Renal Physiology, 08/20/08
Sanchez-Lozada LG et al. - Mild hyperuricemia induced by uricase inhibition causes intrarenal oxidative stress which contributes to the development of the systemic hypertension and the renal abnormalities induced by increased uric acid. Scavenging of the superoxide anion in this setting attenuates the adverse effects induced by hyperuricemia.
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