Choe JY et al. - This cross-sectional study showed that carotid intima–media thickness (IMT) and parameters related with arterial elastic properties in young AS patients without clinically evident cardiovascular risk factors were not different from those of sex- and age-matched healthy controls. Serum levels of TNF-α, IL-6, and MCP-1 did not reflect the degree of carotid subclinical atherosclerosis. Methods
Aim was to assess the correlation between subclinical carotid atherosclerosis and its related clinical parameters in AS pts
28 pts with AS and 27 sex- and age-matched controls
Carotid IMT and parameters related to arterial elastic properties were estimated
Serum levels of TNF-α, IL-6, and monocyte chemoattractant protein-1 (MCP-1) were measured using ELISA
Results
Carotid IMT values and arterial elastic parameters in AS pts showed no significance vs controls
The serum level of IL-6 in AS pts was different compared with controls but not in serum levels of TNF-α and MCP-1
Carotid IMT and all arterial elastic parameters calculated in this study were not associated with serum levels of TNF-α, IL-6, and MCP-1
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