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Holtom PD et al. - The authors retrospectively reviewed 30 patients with hematogenous septic arthritis of the ankle admitted over a 10-year period. C-reactive protein and erythrocyte sedimentation rate were elevated in all patients, but the peripheral white blood cell count was elevated in only 47% of patients. S. aureus is the most common pathogen in septic ankle arthritis and empiric antibiotic therapy is recommended. Adjacent osteomyelitis may be present and a high index of suspicion is necessary in patients with comorbidities.

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