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See Latest ArticlesRecent-onset childhood arthritis - association with Streptococcus pyogenes in a population-based study
Rheumatology, 06/20/08
Riise OR et al. – This study reports that Streptococcus pyogenes was present in 18% of children with arthritis. The patient characteristics, clinical presentation and early disease course in post-streptococcal ReA (PSReA) was different from that of juvenile idiopathic arthritis (JIA) and transient arthritis.
Methods- Study to (i) assess frequency of Streptococcus pyogenes in children with early arthritis and (ii) compare the characteristics in pts with PSReA with those in pts with other types of arthritis
- Population based study: Arthritis pts (n=173) were followed up at 6 wks, 6 mos and 18 mos
- The presence of S. pyogenes was based on throat smear or antibodies
- Echocardiography was performed in the patients with ARF or PSRA
- 18% of children with arthritis tested positive for S. pyogenes
- Percentage of positive tests rose steadily with age and peaked at ages 8–11 (35%)
- 6 wks after admission arthritis was present in 33% of the PSRA pts, which was less frequent than JIA pts but more frequent than transient arthritis pts
- Hip arthritis was more frequent and knee/ankle arthritis, ANA and HLA-B27 were less frequent in PSRA than in JIA
- The PSRA pts were older than those with transient arthritis
- One child with ARF had carditis
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Today in Infectious Arthritis...keeping you current
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The immunobiology of viral arthritides
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Today in Pediatric Rheumatology...keeping you current
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