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Behcet disease;myelodysplastic syndrome Article Summary

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Behcet disease associated with myelodysplastic syndrome
Journal of Clinical Rheumatology (JCR), 06/11/08
Print     Email This Article     Save in My Library   Free Abstract
Lin YC et al. – After reviewing the past case studies, it was suggested that patients with myelodysplastic syndrome and trisomy 8 might be prone to have Behcet disease. Furthermore, more intestinal ulcers but with less eye lesions and arthritis have been noted in patients of Behcet disease with myelodysplastic syndrome than in those without myelodysplastic syndrome.

  • There have been 22 reported cases of Behcet disease associated with myelodysplastic syndrome
  • A case of a 49-year-old woman with Behcet disease is described here who developed myelodysplastic syndrome with abnormal karyotype-trisomy 8
  • This change was not due to immunosuppressive agents because her Behcet disease was not treated with these drugs
  • This is the first report of a case of Behcet disease with pathologic evidence associated with the chronic myelomonocytic leukemia subtype of myelodysplastic syndrome

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