Liu B et al. – The association of Sjogren’s syndrome (SS) with primary biliary cirrhosis (PBC), is significantly higher in patients with than without interstitial lung disease (ILD), which supports the hypothesis that ILD and SS in PBC, may be a causal, not casual, association. Methods
Aim was to determine (i) whether ILD and SS in PBC is a causal or casual association, (ii) whether SS accompanying PBC, could be considered secondary to or associated with PBC
109 consecutive PBC cases were analyzed
Differences of clinical features, histological stages, and serum autoantibodies between the PBC pts with and w/o SS were compared
There were 46 PBC pts with SS and 63 w/o SS, and 11 pts met the criteria of ILD
Results
SS is associated with PBC in the form of secondary SS
The frequency of ILD in PBC pts with SS was 21.7% while only 1.6% in PBC pts w/o SS
ILD in PBC was related to SS, with Spearman’s rank coefficient of 0.330
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