Franklin J et al. – This study supports a positive association between high BMI and total knee replacement (TKR) in both sexes, but for total hip replacement (THR) the association with BMI seems weaker, or for women possibly negligible. Methods
Study to examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement
Pts who had a THR or TKR due to OA were invited to participate
First degree relatives of participating pts served as controls. N=1,473 cases (872 women) and n=1,103 controls (599 women), all born between 1910 and 1939
They were asked to answer a questionnaire including information about height and weight
A randomly selected sample, representative of the Icelandic population, was used as a secondary control group
Results
The odds ratio (OR), adjusted for age, occupation, and the presence of hand OA, for overweight men getting a THR was 1.1 and for obese men the OR was 1.7
The OR for overweight men getting a TKR was 1.7 and for obese men the OR was 5.3
For overweight women the OR for getting a THR was 1.0 and for obese women 1.0
For overweight women the OR for getting a TKR was 1.6 and for obese women the OR was 4.0
See all
