Gibofsky A et al. - A review article to highlight the efficacy and safety of extended-release opioid analgesics utilized in the management plan of chronic pain due to osteoarthritis (OA).
Inadequate pain relief and dissatisfaction with current treatments is a source of frustration and suffering for pts with chronic/persistent pain due to OA
The requirement of multiple doses of commonly used analgesics is inconvenient for many pts
The extended-release opioid analgesics may provide an opportunity for improved patient convenience
However, clinicians must consider AEs profiles, pharmacokinetics, abuse potential, and controlled substance-scheduling status of extended-release opioid analgesics
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