Houssiau FA et al. - This review on the management of lupus nephritis discusses the principles of treatment and the current options for induction and maintenance therapy.
The respective place of mycophenolate mofetil and iv cyclophosphamide are balanced, taking into account efficacy, safety and pts’ perspective
It is anticipated that in a few yrs iv cyclophosphamide, which has been for so long the ‘standard of care’, will be prescribed only in specialized conditions such as documented necrotizing vasculitis