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See Latest ArticlesPossible evolutionary links between immunoglobulin light chains and other proteins involved in amyloidosis
Amyloid The Journal of Protein Folding Disorders, 05/27/08
Stevens FJ - Improvements in sequence comparison tools and strategies, coupled with recent logarithmic increases in the availability of primary structure data, now make it possible to suggest that transthyretin and immunoglobulins may have a common evolutionary origin. In addition, lactadherin, the medin fragment of which accounts for the most common form of human amyloid, also appears to be evolutionarily linked to transthyretin and immunoglobulins.
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