Heinz C et al. – The idiopathic anterior uveitis (IAU) and juvenile idiopathic arthritis (JIA)-associated AU in childhood differ in their clinical course. ANA positivity, presence of uveitis complications at first manifestation, insidious onset, duration over 3 months, best corrected visual acuity (BCVA) of 20/50 or less, and an age of 3 years or younger might help to detect AU associated with JIA Methods
Aim was to identify factors that may help to differentiate JIA-associated AU from the more common IAU before the onset of arthritis
Children with IAU and with JIA-associated AU were analyzed for their demographics, age at onset of uveitis, uveitis course and complications, ocular surgery, antiinflammatory medication, and BCVA
Results
AU was associated with JIA in 88 cases, and was idiopathic in another 49
In the JIA group, 60% of pts were female compared to 47% in the IAU group
Antinuclear antibody (ANA) was more frequent in the JIA group
Insidious uveitis onset occurred more often in JIA than in IAU pts
Persistent uveitis was found in 82% of JIA pts, and in 57% of IAU pts
Median age of AU onset was 5 yrs in JIA and 9 yrs in IAU
Uveitis complications were more frequent in JIA than in IAU pts
During f/u, 69 surgical procedures were performed in the JIA group, and 18 in IAU patients
BCVA was better in the IAU pts at first presentation