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osteomyelitis;Abscess-associated spontaneous pyogenic vertebral Article Summary

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Long-term clinical and radiological magnetic resonance imaging outcome of abscess-associated spontaneous pyogenic vertebral osteomyelitis under conservative management
Seminars in Arthritis and Rheumatism, 05/13/08
Print     Email This Article     Save in My Library   Free Abstract
Euba G et al. – Most patients with abscess-associated spontaneous pyogenic vertebral osteomyelitis (PVO) are cured with a conservative approach. MRI shows STI reduction at ER evaluation. Repeat MRI is probably unnecessary if clinical and laboratory outcomes are satisfactory.

Methods
  • This study evaluates the clinical and MRI outcome of abscess-associated PVO under conservative treatment
  • Pts with spontaneous PVO in whom the initial MRI showed soft-tissue involvement (STI)
  • Treatment according to a medical protocol, clinical and MRI f/u at diagnosis, and at 2 later time points: early response, and late response
  • MRI classified STI as soft-tissue edema (STE) or abscess

Results
  • Of the 27 pts, all had pain, 63% had fever, and 22% had mild neurological impairment
  • The main etiology was Staphylococcus sp (41%)
  • 81% had bacteremia and 67% had epidural/paraspinal abscess
  • Pts received antibiotics for 9 wks, administered orally for 6 wks
  • ER: Three cases failed and general improvement was seen in the remainder
  • MRI showed persistent STI, which diminished in all cases except 1, whereas bone/disc findings remained
  • LR: All pts were cured; 8 reported mild sequelae (30%)
  • MRI still revealed bone/disc abnormalities, but residual STE was infrequent
  • Median f/u was 29 mos

 

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