Mor A et al. - Drug-induced rheumatic syndromes are manifold; offer the clinician an opportunity to define an illness that may remit with discontinuation of the offending agent. Early diagnosis and withdrawal of the drug may prevent unnecessary morbidity and disability. Methods
Strength of associations, diagnostic features and treatment implications, possible mechanisms for drug-induced genesis of rheumatic conditions are assessed
Medline database was reviewed to identify drug-induced arthritic and connective-tissue disease syndromes
A qualitative review was performed and the relevant information was organized
Results
211/357 publications were included in the final analysis
Many drugs were identified as mimicking existing rheumatic conditions, including small molecules and biologic agents
Most commonly reported drug-induced rheumatic conditions were lupus-like syndromes
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