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Article Summary

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Global damage in systemic juvenile idiopathic arthritis: Preliminary early predictors
Journal of Rheumatology, 04/18/08
Print     Email This Article     Save in My Library   Free Abstract
Russo RAG et al. - Articular damage is the main component of global damage in patients with systemic juvenile idiopathic arthritis (sJIA). Early cervical spine involvement and corticosteroid usage may identify patients with sJIA at risk of developing damage.

Methods
  • Aim was to assess damage in sJIA by the use of the Juvenile Arthritis Damage Index (JADI) and to identify early predictors of global, articular, and extraarticular damage
  • 47 pts with sJIA with a disease duration >24 mos were assessed for damage in a cross-sectional evaluation
  • The JADI was administered by 2 pediatric rheumatologists
  • Damage was defined as JADI score >=1
  • Early clinical variables were retrieved from clinical records, and they included demographic, clinical, and laboratory characteristics

Results
  • 43% pts exhibited damage: 38% had articular and 19% extraarticular damage
  • JADI score ranged between 0-24
  • Cervical spine arthritis and corticosteroid usage occurring in the first 6 mos of the disease course were found as predictors of damage
  • Damage scores correlated with number of joints with limited motion, and with functional disability

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