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532-nm and 1064-nm Q-switched Nd:YAG laser therapy for reduction of pigmentation in macular amyloidosis patches
Journal of the European Academy of Dermatology and Venereology, 03/28/08

Ostovari N et al. - The findings of this study showed the net positive effect of Q-switched Nd:YAG laser, either 532 nm or 1064 nm, in pigment reduction of macular amyloidosis patches, but the 532-nm laser was more effective than 1064 laser.

• Objective was to determine the efficiency of Q-switched Nd:YAG laser in reducing the pigmentations due to skin macular amyloidosis
• 20 subjects with macular amyloidosis were treated with Q-switched Nd:YAG laser: 532 nm in one part and with 1064 nm in another part of their plaques
• Assessment of efficiency was done by colorimetric scores
• And also by digital photographs before laser therapy and 8 wks after treatment

• Two lasers were effective in reducing the degree of macular amyloidosis patches pigmentation
• 532 nm was meaningfully more effective than 1064 nm
• Photograph-based analysis showed that 90% of cases treated by 532 nm had good or very good response
• In 1064 nm-treated patches, 60% of cases had the good or very good response

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