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Ankylosing Spondylitis; scintigraphy Article Summary

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The diagnostic value of scintigraphy in assessing sacroiliitis in Ankylosing Spondylitis - a systematic literature research
Annals of Rheumatic Diseases, 02/26/08
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Song IH et al. - In total 99 articles about scintigraphy were found. 25 articles were included into the analysis. Overall sensitivity for scintigraphy to detect sacroiliitis was 51.8% for patients with established AS and 49.4% for patients with probable sacroiliitis. Sensitivity of scintigraphy in AS patients with inflammatory back pain (indicating ongoing inflammation) was 52.7% and in patients with AS and suspected sacroiliitis with magnetic resonance imaging showing acute sacroiliitis (as a gold standard) was 53.2%. In controls with MLBP specificity was 78.3% resulting in LRs not higher than 2.5-3.0. These data as a result of a literature research suggest that scintigraphy of the sacroiliac joints is at the most of limited diagnostic value for the diagnosis of established AS including the early diagnosis of probable / suspected sacroiliitis.
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