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See Latest ArticlesPotential use for IL-1 blockade in the treatment of gout
Nature Reviews Rheumatology , 07/05/07
Several agents are available and generally effective for the treatment of gout; however, many are poorly tolerated, or contraindicated in patients with renal, cardiovascular or gastrointestinal disease. Studies have shown that monosodium urate crystals induce interleukin-1 (IL-1) production, by activation of the NALP3 (cryopyrin) inflammasome, which led investigators from Switzerland to determine whether IL-1 blockade could inhibit inflammation induced by monosodium urate crystals
Today in Basic Science/Genetics...keeping you current
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Decreased circulating CD28-negative T cells in patients with rheumatoid arthritis treated with abatacept are correlated with clinical response
Journal of Rheumatology, 03/19/10
Association study between polymorphisms in selenoprotein genes and susceptibility to Kashin-Beck disease
Osteoarthritis and Cartilage , 03/19/10
Field Synopsis and Synthesis of Genetic Association Studies in Osteoarthritis: The CUMAGAS-OSTEO Information System
American Journal of Epidemiology, 03/19/10
Today in Clinical Pharmacology...keeping you current
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A review of the effect of anticonvulsant medications on bone mineral density and fracture risk
The American Journal of Geriatric Pharmacotherapy, 03/19/10
Severe exfoliative dermatitis caused by strontium ranelate: two cases of a new drug reaction
Age and Aging, 03/19/10
A walking model to assess the onset of analgesia in osteoarthritis knee pain
Osteoarthritis and Cartilage , 03/19/10
Today in Gout and Hyperuricemia...keeping you current
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Pegloticase for chronic gout
Cochrane Reviews, 03/19/10
Gout, Hyperuricemia, and Parkinson’s Disease: A Protective Effect
Current Rheumatology Reports, 03/19/10
Update on Biology: Uric Acid and the Activation of Immune and Inflammatory Cells
Current Rheumatology Reports, 03/18/10
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