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Health-related quality of life, employment and disability in patients with Sjögren's syndrome
Meijer JM et al. – Findings suggest that Sjögren's syndrome (SS) has a large impact on health-related quality of life (HR-QOL), employment and disability.

Methods
  • A comparison of HR-QOL, employment and disability of primary and secondary SS (pSS and sSS) pts with the general Dutch population
  • HR-QOL, employment and disability were evaluated with SF-36 questionnaire and an employment and disability questionnaire in 235 pts
  • Results were compared with Dutch population data matched for sex and age
  • Demographical and clinical data associated with HR-QOL, employment and disability were assessed
Results
  • Response rate was 83%; SS pts scored lower on HR-QOL than the general Dutch population
  • sSS pts scored lower on physical functioning, bodily pain and general health than pSS pts
  • Predictors for reduced HR-QOL were:
    • fatigue, tendomyalgia, articular involvement,
    • use of artificial saliva, use of anti-depressants, comorbidity,
    • male sex and eligibility for disability compensation (DC)
  • Employment was lower and DC rates were higher in SS pts vs Dutch population
[more...]
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