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Risk factors for low BMD in healthy men age 50 years or older: A systematic review
Papaioannou A et al. - Risk factors for low bone mineral density (BMD) and bone loss in healthy men age 50 years or older are age, smoking, low weight, physical/functional limitations, and previous fracture.

Methods
  • Objective was to examine risk factors for BMD and bone loss in healthy men age ≥50 yrs
  • A systematic search in MEDLINE, Cochrane Database of Systematic Reviews, DARE, CENTRAL, CINAHL and Embase, Health STAR

Results
  • 299/642 screened articles required a full review, and 25 remained in the final assessment
  • Consistent risk factors for low BMD/bone loss were: advancing age, smoking, and low weight/weight loss
  • Physical/functional limitations and prevalent fracture were also associated with low BMD/bone loss
  • Evidence was inconsistent or weak for physical activity, alcohol consumption, calcium intake, muscle strength, family history of fracture/osteoporosis, and height/height loss
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