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Morbidity and Mortality in Adult Polymyositis and Dermatomyositis
Current Rheumatology Reports, 03/16/2012
Marie I – The overall mortality ratio in polymyositis/dermatomyositis (PM/DM) patients also remains threefold higher compared with the general population, with cancer, lung, and cardiac complications and infections being the most common causes of deaths. Predictive factors for a poor prognosis in PM/DM patients are older age, involvement of lung and cardiac systems, dysphagia, cancer, and serum myositis–specific antibodies (including coexistent presence of anti–Ro52 and anti–Jo1 antibodies, anti–signal recognition particle antibody, anti–155/140, and anti–CADM–140 antibodies).
