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Partial Response to Anakinra in Life-Threatening Henoch-Schonlein Purpura: Case Report
Pediatric Rheumatology, 08/19/2011
Boyer EM et al. – Henoch–Schonlein purpura is one of the most common forms of systemic vasculitis of childhood.
- The authors report the response to anakinra, the interleukin–1 receptor antagonist, in a 9 year old girl without prior medical problems who developed life–threatening Henoch–Schonlein vasculitis that produced renal failure, pulmonary hemorrhage and vasculitis of the brain.
- Her response supports the theory that interleukin–1 may be an important mediator in this disease.
